Details
| Name | KLOTHO |
| Type | gene |
| Species | Mice |
| Tissue | kidney |
| Experiment Method | NA |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | These results indicate that the increased DNMT1/3a/3b expression might be responsible for the promoter hypermethylation and the suppression of KLOTHO and NRF2 in aging kidneys. |
| Regulation Gene | NA |
| Year | 2022 |
| Pubmed ID | 34874096 |
| Title | Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |