| Name |
DNMT1
|
| Type |
miRNA
|
| Species |
Mouse
|
| Tissue |
cell
|
| Experiment Method |
siRNA Oligos and CD63-pEGFP,RNA-seq,Ladder Rung Test
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Both DNA methylation, mediated by DNA methyltransferases (DNMTs), and histone modifications maintain neuronal function throughout lifespan. Here we provide evidence that DNMT1 function is implicated in the age-related loss of cortical inhibitory interneurons.
|
| Regulation Gene |
DNMT1
|
| Year |
2020
|
| Pubmed ID |
32793592
|
| Title |
DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
null
|