A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p66Shc
Type miRNA
Species Homo sapiens
Tissue microvascular
Experiment Method real-time quantitative polymerase chain reaction and methylated-DNA capture
Up/Down Down
Pro/Anti Anti
Funtion Description Long-term physical activity-induced DNA methylation of p66Shc may represent a putative mechanistic link whereby active lifestyle promotes healthy microvascular ageing.
Regulation Gene p66Shc
Year 2020
Pubmed ID 31610708
Title Physical activity may drive healthy microvascular ageing via downregulation of p66(Shc).
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null