A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name H3K9
Type gene
Species Homo sapiens
Tissue The human placenta and its specialized cytotrophoblasts
Experiment Method NA
Up/Down NA
Pro/Anti Anti
Funtion Description Profiling the extraembryonic epigenome and transcriptome during the 2nd and 3rd trimesters revealed H3K9 trimethylation overlapping deeply DNA hypomethylated domains with reduced gene expression and compartment-specific patterns that illuminated their functions
Regulation Gene NA
Year 2021
Pubmed ID 33891899
Title Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease
Drug NA
Disease severe preeclampsia.
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA