A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MEG8
Type miRNA
Species Homo sapiens
Tissue human umbilical vein endothelial cells;human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes
Experiment Method RT-qPCR
Up/Down Down
Pro/Anti Anti
Funtion Description MEG8 knockdown resulted in a 1.8-fold increase in senescence, suggesting MEG8 might be protective during aging.
Regulation Gene miRNA-370-3p and miRNA-494-3p
Year 2022
Pubmed ID 35611612
Title The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA