Details
| Name | circ-Sirt1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | vascular |
| Experiment Method | Western Blot Analysis,qRT-PCR,FISH,Immunofluorescence Staining,RIP,ChIP |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Overexpression of circ-Sirt1 delayed Ang II-induced VSMC senescence in vitro and ameliorated neointimal hyperplasia in vivo. |
| Regulation Gene | p53 |
| Year | 2021 |
| Pubmed ID | 34977164 |
| Title | circ-Sirt1 Decelerates Senescence by Inhibiting p53 Activation in Vascular Smooth Muscle Cells, Ameliorating Neointima Formation |
| Drug | NA |
| Disease | vascular disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |