A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FKRP
Type gene
Species Mus musculus
Tissue FKRPP448L mice
Experiment Method Immunohistochemical and Western Blot
Up/Down Up
Pro/Anti Pro
Funtion Description A recombinant adeno-associated virus (AAV) serotype 9 vector expressing human FKRP (AAV9-FKRP) was systemically administered to FKRPP448L mice at 5 weeks of age, when early onset of the disease is evidenced.Additional studies assessed the impact of FKRP g
Regulation Gene NA
Year 2018
Pubmed ID 30417025
Title Dose-Dependent Effects of FKRP Gene-Replacement Therapy on Functional Rescue and Longevity in Dystrophic Mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA