A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name tra-1
Type gene
Species C. elegans
Tissue NA
Experiment Method RT-qPCR,Western blotting
Up/Down Down
Pro/Anti Pro
Funtion Description By contrast, sulforaphane did not prolong lifespan and healthspan when tra-1 or daf-16 was inhibited by RNA interference or when worms with a loss-of-function mutation of the tra-1 or daf-16 genes were used.
Regulation Gene NA
Year 2021
Pubmed ID 34926464
Title Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA