Details
| Name | daf-16 |
| Type | gene |
| Species | C. elegans |
| Tissue | NA |
| Experiment Method | RT-qPCR,Western blotting |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | By contrast, sulforaphane did not prolong lifespan and healthspan when tra-1 or daf-16 was inhibited by RNA interference or when worms with a loss-of-function mutation of the tra-1 or daf-16 genes were used. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34926464 |
| Title | Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |