A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name S100A8
Type gene
Species Mice
Tissue mesenteric lymph nodes
Experiment Method q-PCR
Up/Down Up
Pro/Anti NA
Funtion Description Analysis of ileal tight junctional proteins and inflammatory marker gene expression revealed no difference in Ocln, Tjp1, Il6, or Tnf expression among all groups, but 2.3 and 2.9-fold upregulation of S100a8 and S100a9, respectively, in aged burn-injured mice relative to both young groups and aged sham-injured mice (p < 0.05).
Regulation Gene NA
Year 2022
Pubmed ID 34915110
Title Advanced age exacerbates intestinal epithelial permeability after burn injury in mice
Drug NA
Disease NA
Environment Factors burn
Circulating NA
Variant NA
High-throughput NA