Details
| Name | Cldn4 |
| Type | gene |
| Species | Mice |
| Tissue | blood |
| Experiment Method | qRT-PCR |
| Up/Down | Down |
| Pro/Anti | NA |
| Funtion Description | In the parabiosis experiment, we observed that the high expression of genes encoding secretory mucin proteins (Muc2 and Muc3) and the significant decrease in genes encoding barrier-forming tight junction proteins (Zo-1, Cldn3 and Cldn4) in isochronic aged mice |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34906228 |
| Title | Ageing and rejuvenation models reveal changes in key microbial communities associated with healthy ageing |
| Drug | Akkermansia |
| Disease | NA |
| Environment Factors | co-housing |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |