A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Formin 2
Type gene
Species Homo sapiens
Tissue EDTA blood samples
Experiment Method Behavior analysis;Cannulation and siRNA injection
Up/Down Down
Pro/Anti Pro
Funtion Description Young mice lacking the Fmn2 gene exhibit PTSD-like phenotypes and corresponding impairments of synaptic plasticity, while the consolidation of new memories is unaffected. However, Fmn2 mutant mice develop accelerated age-associated memory decline that is
Regulation Gene NA
Year 2017
Pubmed ID 28768717
Title Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia
Drug NA
Disease Alzheimer's disease
Environment Factors NA
Circulating 1
Variant NA
High-throughput GSE100070