Details
| Name | P16 |
| Type | gene |
| Species | Mice |
| Tissue | ovaries |
| Experiment Method | NA |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Additionally, the protein and gene expressions of P16 of ovaries were significantly reduced in 60WN group than in 60WC group. the mitochondria biogenesis, autophagy level, and proteases activity enhanced in granulosa cells after 20-week-administration of NMN. |
| Regulation Gene | NA |
| Year | 2022 |
| Pubmed ID | 34801690 |
| Title | Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the mitophagy level of granulosa cells in mice |
| Drug | Nicotinamide mononucleotide |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |