Details
| Name | Kdm6a |
| Type | gene |
| Species | Mice |
| Tissue | HSPCs |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | emale Kdm6a-knockout (KO) mice have an age-dependent expansion of their HSPCs with aberrant self-renewal, but they did not differentiate normally into downstream progeny. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34780480 |
| Title | Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype |
| Drug | NA |
| Disease | AML |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |