A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO
Type gene
Species Fly Strains
Tissue NA
Experiment Method qRT-PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Studies in Drosophila also support a non-cell-autonomous effect of FOXO on insulin signaling. Overexpression of FOXO in the fat body reduces expression of Drosophila insulin-like peptide 2 (dilp2) in brain neurons and extends lifespan.
Regulation Gene NA
Year 2007
Pubmed ID 17895391
Title FOXO and insulin signaling regulate sensitivity of the circadian clock to oxidative stress.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA