A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO1
Type gene
Species Dog
Tissue Heart
Experiment Method DNA microarray analyses
Up/Down Up
Pro/Anti Anti
Funtion Description Overexpression of either Sirt1 or constitutively active FoxO1a in cultured cardiac myocytes stimulated expression of catalase, whereas upregulation of catalase was inhibited in the presence of dominant negative FoxO1a. These results suggest that FoxO1a pl
Regulation Gene NA
Year 2007
Pubmed ID 17446436
Title Sirt1 regulates aging and resistance to oxidative stress in the heart.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA