A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CFHR3
Type CNV
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Eight unique combinations of copy number variation were observed in the 813 subjects. Combined deletion of CFHR3 and CFHR1 was protective (OR=0.47, 95% confidence interval 0.36-0.62) against age-related macular degeneration and was observed in 88 (82 [18.
Regulation Gene CFHR3
Year 2011
Pubmed ID 21850184
Title Copy number variation in the complement factor H-related genes and age-related macular degeneration
Drug NA
Disease age-related macular degeneration
Environment Factors NA
Circulating 1
Variant CNV
High-throughput NA