A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TSG-101
Type gene
Species Homo sapiens
Tissue vascular smooth muscle cells
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description First, senescent hVSMC-derived exosomes tended to cluster together during replicative senescence and the molecular weight of the exosomal protein tumor susceptibility gene 101 (TSG-101) increased relative to the intracellular TSG-101, suggesting potential posttranslational modifications of exosomal TSG-101.
Regulation Gene NA
Year 2021
Pubmed ID 34506226
Title Intracellular and exosomal microRNAome profiling of human vascular smooth muscle cells during replicative senescence
Drug NA
Disease Vascular aging
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA