A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO1
Type gene
Species Mus musculus
Tissue Seven week-old male SAMP1 mice and 27 week-old male SAMR1 and SAMP10 mice;Immune cells in SPNs and MLNs
Experiment Method FACS;qRT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description In SAMP10 mice, in addition to preventing a decrease in the nave T cell ratio, aging-associated skin thinning was suppressed histologically and the expression of representative tight junction genes, such as Claudin-1 and Zo-1, was increased. Furthermore,
Regulation Gene NA
Year 2018
Pubmed ID 29964182
Title Long-term administration of pDC stimulative lactic acid bacteria, Lactococcus lactis strain Plasma, prevents immune-senescence and decelerates individual senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating LC-Plasma
Variant NA
High-throughput NA