A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name KL
Type gene
Species Homo sapiens
Tissue normal human dermal fibroblasts
Experiment Method NA
Up/Down Up
Pro/Anti Anti
Funtion Description Centcyamine activates the expression of the gene KL and the related protein Klotho in dermal fibroblasts.
Regulation Gene NA
Year 2021
Pubmed ID 34403147
Title The alkaloid centcyamine increases expression of klotho and lamin B1, slowing the onset of skin ageing in vitro and in vivo
Drug Centcyamine
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA