A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Trf2
Type gene
Species Mice
Tissue ovarian follicles
Experiment Method qRT-PCR,Telomerase activity assay
Up/Down Down
Pro/Anti Pro
Funtion Description We revealed that the Tert, Terc, Trf1, Trf2, and Pot1a gene expression (P < 0.001) and TERT protein (P < 0.01) levels significantly decreased in certain ovarian follicles of the aged group when compared to those of the adult group.
Regulation Gene NA
Year 2021
Pubmed ID 34330985
Title Telomere associated gene expression as well as TERT protein level and telomerase activity are altered in the ovarian follicles of aged mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA