Details
| Name | Cplx1 |
| Type | gene |
| Species | Mice |
| Tissue | hippocampus |
| Experiment Method | Real-Time Polymerase Chain Reaction,Northern Dot Blot Arrays |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Complexin 1 (Cplx1), SNAP25 (Snap25), syntaxin 1A (Stx1a), neurexin 1 (Nrxn1), neurofilament light (Nefl), and synaptotagmin 1 (Syt1) in the hippocampus, and VAMP1 (Vamp1) and neurexin 1 (Nrxn1) in the cortex were all significantly reduced in 12-month-old mice. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34305524 |
| Title | Age-Related Transcriptional Deregulation of Genes Coding Synaptic Proteins in Alzheimers Disease Murine Model: Potential Neuroprotective Effect of Fingolimod |
| Drug | NA |
| Disease | Alzheimers disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | V717I |
| High-throughput | NA |