Details
| Name | HDAC2 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | dermal fibroblasts |
| Experiment Method | real time PCR,Western blot analysis,ELISA |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Moreover, treatment with SAHA, a histone deacetylase inhibitor (HDACi) also known as Vorinostat, or the specific downregulation of HDAC2 or HDAC7 by siRNA, induces the appearance of senescence biomarkers of dermal fibroblasts. |
| Regulation Gene | NA |
| Year | 2021 |
| Pubmed ID | 34253688 |
| Title | HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |