Details
| Name | FOXO3 |
| Type | gene |
| Species | Mus musculus |
| Tissue | Lung |
| Experiment Method | Immunoprecipitation,Immunoblot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Increased cellular senescence in lungs of COPD patients. SIRT1 activation by both genetic overexpression and a selective pharmacological activator, SRT1720, attenuated stress-induced premature cellular senescence and protected against emphysema induced by |
| Regulation Gene | NA |
| Year | 2012 |
| Pubmed ID | 22546858 |
| Title | SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |