Details
| Name | FOXO3a |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Human bone marrow |
| Experiment Method | siRNA transfection;quantitative real-time PCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | In vitro, the antioxidant capacity of old hMSCs (O-hMSCs) was increased after SIRT3 overexpression using a gene transfection technique, while the antioxidant capacity of young hMSCs (Y-hMSCs) was decreased by SIRT3 silencing.The levels of forkhead box O3a |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30091830 |
| Title | Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |