A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PTX3
Type gene
Species Homo sapiens
Tissue tendon
Experiment Method CITE-sequencing,Surface proteomic analysis
Up/Down Up
Pro/Anti Pro
Funtion Description We applied next generation CITE-sequencing; combining surface proteomics with in-depth, unbiased gene expression analysis of more 6400 single cells ex vivo from 11 chronically tendinopathic and 8 healthy human tendons. Immunohistochemistry validated the single cell findings.
Regulation Gene PTX3
Year 2020
Pubmed ID 32883960
Title Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon.
Drug NA
Disease Chronic tendinopathy
Environment Factors NA
Circulating NA
Variant NA
High-throughput null