Details
| Name | p53 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | muscle |
| Experiment Method | RNA-seq |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We used RNA-sequencing (RNA-seq) to identify genes associated with atrophy after TKA with and without EAAs. Analysis of overrepresented gene-ontology terms revealed that p53 signaling and the cytokine-cytokine receptor pathways were highly upregulated after TKA. |
| Regulation Gene | MDM2 |
| Year | 2020 |
| Pubmed ID | 32881622 |
| Title | Essential amino acid supplementation alters the p53 transcriptional response and cytokine gene expression following total knee arthroplasty. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |