Details
| Name | sod-3 |
| Type | gene |
| Species | C. elegans |
| Tissue | NA |
| Experiment Method | NA |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Here, we show that p38 MAPK signaling regulates induction of not only the direct expression of sod-1, -2 and -4 but also the indirect modulation of DAF-16 targets, such as sod-3 and -5 genes. Moreover, a SKN-1 target, the insulin peptide gene ins-5, partially mediates the expression of DAF-16 targets via p38 MAPK signaling. |
| Regulation Gene | sod-3 |
| Year | 2020 |
| Pubmed ID | 32875124 |
| Title | Interaction between the ins/IGF-1 and p38 MAPK signaling pathways in molecular compensation of sod genes and modulation related to intracellular ROS levels in C. elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |