A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Klotho
Type gene
Species Mouse
Tissue NA
Experiment Method immunohistochemical,Western blotting
Up/Down Up
Pro/Anti Pro
Funtion Description Firstly, Western blotting and immunohistochemical staining were applied to detect the protein expression of Klotho in the renal tissues of diabetic and non-diabetic mice of different ages.
Regulation Gene Klotho
Year 2020
Pubmed ID 32869607
Title Anti-aging gene Klotho ameliorates diabetic nephropathy in mice by inhibiting FGF2 signaling pathway.
Drug inhibiting FGF2
Disease diabetic nephropathy
Environment Factors NA
Circulating NA
Variant NA
High-throughput null