Details
| Name | klotho |
| Type | gene |
| Species | Mouse |
| Tissue | kidney |
| Experiment Method | NA |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Klotho-haplodeficient (KL+/-) mice and WT mice were used. We found that Klotho haplodeficiency impaired kidney function as evidenced by significant increases in plasma urea and creatinine and a decrease in urinary creatinine in KL+/- mice. |
| Regulation Gene | klotho |
| Year | 2020 |
| Pubmed ID | 32863229 |
| Title | In vivo AAV delivery of glutathione reductase gene attenuates anti-aging gene klotho deficiency-induced kidney damage. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |