A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Myh11
Type gene
Species Homo sapiens
Tissue multipotent mesenchymal progenitor cells,smooth muscle cells
Experiment Method hyperphosphatemic inorganic phosphate (Pi) treatment
Up/Down NA
Pro/Anti NA
Funtion Description undifferentiated cells calcified in response to hyperphosphatemic inorganic phosphate (Pi) treatment suggesting that a single cell-type (progenitor cells or differentiated cells) may not be the sole cause of the process. We also demonstrated that Vitamin K, which is the matrix gla protein activator, had a protective role against calcification in engineered vascular tissues.
Regulation Gene Myh11
Year 2020
Pubmed ID 32853805
Title The effects of progenitor and differentiated cells on ectopic calcification of engineered vascular tissues.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null