A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO3a
Type gene
Species Homo sapiens
Tissue Blood
Experiment Method PCR,other
Up/Down NA
Pro/Anti Anti
Funtion Description Genetic variation within the FOXO3A gene was strongly associated with human longevity. The OR for homozygous minor vs. homozygous major alleles between the cases and controls was 2.75 (P = 0.00009; adjusted P = 0.00135). Long-lived men also presented seve
Regulation Gene NA
Year 2008
Pubmed ID 18765803
Title FOXO3A genotype is strongly associated with human longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA