A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO3a
Type gene
Species Homo sapiens
Tissue human melanoma MNT1 cell line
Experiment Method immunofluorescence;Antioxidant activity assay;Determination of melanin levels and tyrosinase enzymatic activity assay
Up/Down NA
Pro/Anti NA
Funtion Description A 7-d treatment with ginseng berry extract reduced melanin accumulation and tyrosinase activity more than ginseng root extract. These results may be due to the active compound of the ginseng berry, syringaresinol. The antimelanogenic activity was strongly
Regulation Gene NA
Year 2017
Pubmed ID 28701867
Title Effects of Korean ginseng berry on skin antipigmentation and antiaging via FoxO3a activation
Drug Korean ginseng berry
Disease melanoma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA