A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name KDM6A
Type Histone methylation
Species Mouse
Tissue second X chromosome
Experiment Method NA
Up/Down NA
Pro/Anti NA
Funtion Description we varied sex chromosome dosage. With or without a Y chromosome, hAPP mice with one X chromosome showed worse mortality and deficits than did those with two X chromosomes.
Regulation Gene KDM6A
Year 2020
Pubmed ID 32848093
Title A second X chromosome contributes to resilience in a mouse model of Alzheimers disease.
Drug NA
Disease Alzheimers disease.
Environment Factors NA
Circulating NA
Variant NA
High-throughput null