A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PRDM8
Type miRNA
Species Homo sapiens
Tissue blood
Experiment Method DNA methylation analysis,BBA-seq,CRISPR/Cas9 technology
Up/Down Up
Pro/Anti Pro
Funtion Description To gain insight into the functional relevance of PRDM8, we used CRISPR/Cas9 technology to generate induced pluripotent stem cells (iPSCs) with heterozygous and homozygous knockout.
Regulation Gene PRDM8
Year 2020
Pubmed ID 32819411
Title PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation.
Drug null
Disease DKC,AA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null