A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CD62L
Type miRNA
Species Mouse
Tissue blood and heart
Experiment Method single-cell transcriptomics,cell surface epitope detection by sequencing ,CITE-seq
Up/Down Up
Pro/Anti Pro
Funtion Description Cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) analysis in blood and heart revealed that while circulating neutrophils undergo a process of aging characterized by loss of surface CD62L and upregulation of Cxcr4, heart infiltrating neutrophils acquired a unique SiglecFhi signature.
Regulation Gene CD62L
Year 2020
Pubmed ID 32811295
Title Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction.
Drug NA
Disease myocardial infarction
Environment Factors NA
Circulating NA
Variant NA
High-throughput null