A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-483-3p
Type promoter
Species Homo sapiens
Tissue hADSCs
Experiment Method Dual-luciferase reporter assays
Up/Down Up
Pro/Anti Pro
Funtion Description Dual-luciferase reporter assays identified insulin-like growth factor-1 (IGF1) as the target gene of miR-483-3p. IGF1 inhibition confirmed its inhibitory effects on replicative senescence in hADSCs.
Regulation Gene miR-483-3p
Year 2020
Pubmed ID 32805717
Title MiR-483 induces senescence of human adipose-derived mesenchymal stem cells through IGF1 inhibition.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null