A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FZO1
Type gene
Species Saccharomyces cerevisiae
Tissue NA
Experiment Method PCR
Up/Down Down
Pro/Anti Anti
Funtion Description we have also discovered that deletion of FZO1 reduces mitophagy. Mitochondrial dysfunction elicits a compensatory retrograde response that extends replicative lifespan. Furthermore, the MDARR engages the mitophagy receptor Atg32 on the mitochondrial
Regulation Gene NA
Year 2019
Pubmed ID 30298458
Title Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA