Details
| Name | PEX5 |
| Type | gene |
| Species | Mouse |
| Tissue | brain homogenates |
| Experiment Method | RNAScope and real-time qPCR analyses,Immunohistochemistry assays |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | we first determined the amount of PEX5, in brain homogenates from young and aged wild-type mice of both sexes. PEX5 protein was decreased in aged male brains, but this reduction was not significant in female brains. RNAScope and real-time qPCR analyses showed that Pex5 mRNA was also reduced in aged male brain cortices, but not in females. |
| Regulation Gene | PEX5 |
| Year | 2020 |
| Pubmed ID | 32777345 |
| Title | Aging lowers PEX5 levels in cortical neurons in male and female mouse brains. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |