Details
| Name | ZNF746/PARIS |
| Type | gene |
| Species | Mice |
| Tissue | myoblasts |
| Experiment Method | FoxO1/p21 |
| Up/Down | up |
| Pro/Anti | pro |
| Funtion Description | PARIS is expressed in myoblasts and decreased during differentiation. PARIS overexpression decreased both proliferation and differentiation of myoblasts without inducing cell death, whereas PARIS depletion enhanced myoblast differentiation. |
| Regulation Gene | ZNF746/PARIS |
| Year | 2020 |
| Pubmed ID | 32398756 |
| Title | ZNF746/PARIS overexpression induces cellular senescence through FoxO1/p21 axis activation in myoblasts. |
| Drug | antioxidant Trolox |
| Disease | Parkinsons |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |