A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method Gene-environment interaction analysis
Up/Down NA
Pro/Anti NA
Funtion Description The aim of this study was to investigate genetic variants that are associated with season of birth programming and longitudinal chronotype change. Longitudinal sleep timing and genotype data from 1449 participants were collected for up to 27 years. Gene-environment interaction analysis was performed for 445 candidate single nucleotide polymorphisms that have previously been associated with chronotype. Associations were tested using linear mixed model.
Regulation Gene SIRT1
Year 2020
Pubmed ID 32371234
Title Interactions between season of birth, chronological age and genetic polymorphisms in determining later-life chronotype.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null