A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Chsy1
Type gene
Species Rat
Tissue NA
Experiment Method NA
Up/Down Down
Pro/Anti Anti
Funtion Description Consistent with this function, the Chsy1 mutation dramatically decreases chondroitin sulfate GAGs in the retina and hippocampus. In addition, macrophage and neutrophil populations appear significantly altered in the bone marrow and spleen of skt mice, suggesting an important role for CHSY1 in the functioning of these immune cell types.
Regulation Gene Chsy1
Year 2020
Pubmed ID 31754016
Title Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in skt Mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null