A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name APOEE4
Type gene
Species Homo sapiens
Tissue neure
Experiment Method NA
Up/Down NA
Pro/Anti NA
Funtion Description Secondary analyses revealed a negative relationship between cACC CTH and executive functioning in E4+ and a positive relationship in E4-. Findings suggest the presence of an E4-related pattern of increased CTH and reduced CBF in the ACC that is associated with biomarkers of neurodegeneration and subtle decrements in cognition.
Regulation Gene APOEE4
Year 2020
Pubmed ID 31743999
Title Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEE4 Carriers.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null