A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name LTL
Type methylation
Species Homo sapiens
Tissue NA
Experiment Method quantitative polymerase chain reaction
Up/Down Up
Pro/Anti Pro
Funtion Description Young adults with PWS have significantly shorter median LTL compared to age-matched healthy young adults and GH-treated young adults born SGA. The shorter telomeres might play a role in the premature aging in PWS, independent of GH. Longitudinal research is needed to determine the influence of LTL on aging in PWS.
Regulation Gene LTL
Year 2020
Pubmed ID 31689713
Title Evidence for Accelerated Biological Aging in Young Adults with Prader-Willi Syndrome.
Drug NA
Disease PWS
Environment Factors NA
Circulating NA
Variant NA
High-throughput null