A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ORP3
Type miRNA
Species Homo sapiens
Tissue NA
Experiment Method gene knockout
Up/Down Down
Pro/Anti Anti
Funtion Description The knockdown of the three strongest selected candidate genes (ORP3, GJB3, and RXFP1) enhances the malignant transformation of human fibroblasts in culture.
Regulation Gene ORP3
Year 2020
Pubmed ID 31659255
Title Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null