A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GJB3
Type miRNA
Species Homo sapiens
Tissue NA
Experiment Method gene knockout
Up/Down Down
Pro/Anti Anti
Funtion Description The knockdown of the three strongest selected candidate genes (ORP3, GJB3, and RXFP2) enhances the malignant transformation of human fibroblasts in culture.
Regulation Gene GJB3
Year 2021
Pubmed ID 31659256
Title Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp4 as a B-cell lymphoma suppressor.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null