A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ALOX5
Type miRNA
Species Rat
Tissue NA
Experiment Method gene knockout
Up/Down Up
Pro/Anti Pro
Funtion Description The mouse Alox5 triple mutant functions as arachidonic acid 15-lipoxygenating enzyme, which also forms 12S-hydroxy and 8S-hydroxy arachidonic acid.
Regulation Gene ALOX5
Year 2020
Pubmed ID 31642348
Title Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput null