Details
| Name | Tmem119 |
| Type | somatic mutation |
| Species | Rat |
| Tissue | neure |
| Experiment Method | CRISPR/Cas9 |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Functionally, using an acute injury model, we measured time-lapse activation of tdTomato-labeled microglia by transcranial two-photon microscopy in live Tmem119tdTomato/+ mice. Taken together, the Tmem119-tdTomato reporter mouse model is a valuable tool to specifically study the role of microglia in health and disease. |
| Regulation Gene | Tmem119 |
| Year | 2020 |
| Pubmed ID | 31604143 |
| Title | A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |