Details
| Name | CYP1A1 |
| Type | TF |
| Species | Homo sapiens,Rat Rattus |
| Tissue | skin |
| Experiment Method | melanocyte 3D coculture model |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | In vitro and ex vivo studies clearly demonstrated that diglucosyl gallic acid (active A) and the formulation complex inhibited pollution mediated MMP1 protein, CYP1A1 gene expression, and IL-6 protein secretion, while caprylic/capric triglyceride, diacetyl boldine (active B) had anti-melanogenic effect in in vitro primary melanocyte monoculture and 3D spheroid model. |
| Regulation Gene | CYP1A1 |
| Year | 2020 |
| Pubmed ID | 31584241 |
| Title | A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | null |