A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ERCC
Type TF
Species Homo sapiens
Tissue NA
Experiment Method WES ,Sanger sequencing
Up/Down Up
Pro/Anti Pro
Funtion Description Two compound, heterozygous ERCC excision repair 6, chromatin remodelling factor (ERCC6) gene mutations were detected in the proband by WES and confirmed by Sanger sequencing, comprising a known paternal nonsense mutation
Regulation Gene ERCC
Year 2020
Pubmed ID 31558084
Title Two heterozygous mutations in the ERCC6 gene associated with Cockayne syndrome in a Chinese patient.
Drug NA
Disease CS
Environment Factors NA
Circulating NA
Variant NA
High-throughput null